Factors Affecting Polyphenol Biosynthesis in Wild and Field Grown St. John’s Wort (Hypericum perforatum L. Hypericaceae/Guttiferae)

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Factors affecting polyphenol biosynthesis in wild and field grown St. John's Wort (Hypericum perforatum L. Hypericaceae/Guttiferae).

The increasing diffusion of herbal products is posing new questions: why are products so often different in their composition and efficacy? Which approach is more suitable to increase the biochemical productivity of medicinal plants with large-scale, low-cost solutions? Can the phytochemical profile of a medicinal plant be modulated in order to increase the accumulation of its most valuable con...

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St. John's wort (Hypericum perforatum) and warfarin: Dangerous liaisons!

An 85-year-old male patient with a history of hypertension, old anterior wall myocardial infarction and atrial fibrillation was placed on warfarin one year previously. However, he did not comply with regular international normalized ratio (INR) measurements, but kept taking warfarin (5 mg) on a daily basis for almost a year without any problems. After watching a television program about herbal ...

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St John’s wort (Hypericum perforatum)-induced psychosis: a case report

BACKGROUND St John's wort (Hypericum perforatum) has been known for centuries for its therapeutic properties and its efficacy as an antidepressant has been confirmed by a growing body of evidence. During the last two decades it has also come to prominence with a wider public, due to advertising efforts across Europe and United States of America. However, its availability without prescription, a...

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St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties.

The chemical composition of St. John's wort has been well-studied. Documented pharmacological activities, including antidepressant, antiviral, and antibacterial effects, provide supporting evidence for several of the traditional uses stated for St John's wort. Many pharmacological activities appear to be attributable to hypericin and to the flavonoid constituents; hypericin is also reported to ...

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Effects of St John's wort (Hypericum perforatum L.) extracts on epileptogenesis.

The purpose of this study was to investigate the effects of treatment with water, n-butanol and ether extracts of Hypercom perforatum L. on epileptogenesis in rabbits. Animals from the control group received solvent-ethanol, and the kindling model of epilepsy was used. Epileptic focus was induced in Chinchilla rabbits by stimulation of the hippocampus. The following parameters were determined: ...

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ژورنال

عنوان ژورنال: Molecules

سال: 2009

ISSN: 1420-3049

DOI: 10.3390/molecules14020682